DISCO module 2 is concerned with application and the implementation of genetic intervention pipelines. It shall be ensured that the very latest procedures are in place to facilitate rapid and efficient metabolic engineering and molecular breeding. To address this requirement a dedicated enabling technologies platform will operate.
The DISCO partners have vast experience in the metabolic engineering of biochemical pathways, in some cases pioneering the technology and bringing the technology, when in its infancy, to the market place.
An important activity within this module will be to transfer this technology to new pathways and regulatory mechanisms, creating a pipeline of efficient metabolic engineering activity. The approach will extend the expertise gained to other high value products and ensure improvements in the technologies are incorporated into strategies at the earliest opportunity. In addition to the metabolic engineering approaches which are essential when no terrestrial or viable sources exist, molecular breeding procedures will be implemented. Significant investments have generated vast exploitable genetic resources in Solanaceae and these resources will be used in the DISCO project to facilitate molecular breeding pipelines for high value bioactive molecules of interest.